Platelet studies in autism spectrum disorder patients and first-degree relatives
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چکیده
منابع مشابه
Commentary on “Platelet Studies in Autism Spectrum Disorder Patients and First-Degree Relatives”
BACKGROUND Platelets have been proven to be a useful cellular model to study some neuropathologies, due to the overlapping biological features between neurons and platelets as granule secreting cells. Altered platelet dense granule morphology was previously reported in three autism spectrum disorder (ASD) patients with chromosomal translocations that disrupted ASD candidate genes NBEA, SCAMP5, ...
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Our aim was to observe the induction of panic attacks by a hyperventilation challenge test in panic disorder patients (DSM-IV) and their healthy first-degree relatives. We randomly selected 25 panic disorder patients, 31 healthy first-degree relatives of probands with panic disorder and 26 normal volunteers with no family history of panic disorder. All patients had no psychotropic drugs for at ...
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BACKGROUND Stimulus-related γ-band oscillations, which may be related to perceptual binding, are reduced in people with autism spectrum disorders (ASD). The purpose of this study was to examine auditory transient and steady-state γ-band findings in first-degree relatives of people with ASD to assess the potential familiality of these findings in ASD. METHODS Magnetoencephalography (MEG) recor...
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OBJECTIVES Intestinal permeability (IPT) was investigated in patients with autism as well as in their first-degree relatives to investigate leaky gut hypothesis. Faecal calprotectin (FC) was also measured in patients with autism, either with or without gastrointestinal symptoms, and in their first-degree relatives. PATIENTS AND METHODS IPT results, assessed by means of the lactulose/mannitol ...
متن کاملNeurobehavioral abnormalities in first-degree relatives of individuals with autism.
CONTEXT Studying sensorimotor and neurocognitive impairments in unaffected family members of individuals with autism may help identify familial pathophysiological mechanisms associated with the disorder. OBJECTIVE To determine whether atypical sensorimotor or neurocognitive characteristics associated with autism are present in first-degree relatives of individuals with autism. DESIGN Case-c...
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ژورنال
عنوان ژورنال: Molecular Autism
سال: 2015
ISSN: 2040-2392
DOI: 10.1186/s13229-015-0051-y